Research

Reliable AI starts
with testable claims.

We test uncertainty and risk control on public datasets, and develop the theory for AI systems that change.

12Benchmark studies
2Method investigations

Inside a validation · Chákṣu → RIGA

Same model.
New population.
Different risk.

Local recalibration reduced omitted anatomy on a new dataset, at the cost of larger regions.

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Validation studies

Different datasets. Precise questions.

Completed experiments that test the technology. Each has its own reference, risk definition and scope.

Language & human judgment

HumAID

How much review can a calibrated policy remove?

13.88% removed from immediate review; 3.39% priority content within that subset.

GoEmotions

What does a stricter error limit cost in automation?

3.86% to 35.86% auto-tagging as the chosen limit moves from 5% to 20%.

TweetEval

One sentiment model. Different error budgets.

6.39% to 43.41% auto-tagging across the supported sentiment budgets.

Evidence & time

NEISS

More evidence makes calibration more stable.

4.93% set misses; a single label on 50.50% of 10,000 held-out records.

NTSB

What happens when a calibrated policy gets older?

6.43%, 4.63% and 5.40% observed set misses for three calibration vintages.

Prediction sets & expert references

HAM10000

Control missed labels without returning every label.

4.49% reference-label misses; 2.24 labels per lesion out of seven.

CheXpert

Zero observed misses still has a cost.

0 misses in 60 studies; only 8 studies received a single answer.

CBIS-DDSM

Make the cost of a decisive answer visible.

4.21% reference misses; one answer for 24.91% of participants.

LIDC-IDRI

Preserve disagreement instead of inventing one truth.

2.75% patient-average rating exclusion; 3.79 of five ratings retained.

Spatial uncertainty & transfer

Chákṣu

How much anatomy can a predicted region omit?

5.37% observed omission; regions averaged 1.28× the expert cup area.

Chákṣu → RIGA

A model can transfer while its calibration does not.

19.44% to 3.45% omission after local recalibration, with 4.88× region area.

PolypGen

Can adaptive regions stay precise under risk control?

33.22% versus 48.91% image area for two calibrated methods at a 5% target.

Method investigations · what did not support automation

The target

The risk quantity and limit chosen before evaluation.

The result

Observed errors and the cost in review, set size or region area.

The guarantee

The statistical statement supported by calibration, under its assumptions.

Publications

From predictions to whole systems.

MICCAI 2026 · UNSURE workshop · Research paper

Sequential Conformal Safety for Trustworthy Clinical Decision Pathways in Ophthalmology

Propagating uncertainty through multi-stage clinical pathways while preserving safe alternatives.

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NeurIPS 2025 · GenAI for Health workshop · Position paper

Ophthalmology as a Lens for Trustworthy GenAI in Europe

A perspective on uncertainty-aware AI, clinical trust and the European setting.

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Research agenda

Guarantees for AI
that keeps changing.

Our scientific program for deployed, adaptive AI systems.

Explore our research agenda

Work on the foundations with us.

We welcome research conversations and collaborations.

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